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Medical Science Liaison - Movement Disorders

April 29, 2026

Location: This position may be performed remotely, but requires the flexibility and willingness to travel as needed. The Opportunity Praxis is seeking a field-based Medical Science Liaison (MSL) to support Medical Affairs activities for ulixacaltimide during prelaunch and potential launch. This role is focused on building trusted scientific partnerships, delivering high-quality scientific exchange, and generating actionable insights to inform medical strategy and ensure clinical readiness. This is a field-facing, development-oriented role where you will engage healthcare professionals and investigators to communicate emerging clinical data, deepen disease state understanding, and identify unmet needs and potential barriers to patient care. You will work closely with cross-functional partners to ensure aligned and compliant execution of prelaunch and launch activities. Success in this role requires strong scientific curiosity, effective communication skills, and the ability to operate with guidance while building confidence and independence in the field in a fast-paced environment. Primary Responsibilities <ul> <li>Build and maintain scientific relationships with healthcare professionals, investigators, and key opinion leaders to support Medical Affairs objectives </li> <li>Deliver accurate, balanced, and compliant scientific exchange on disease state, clinical data, and the ulixacaltimide profile </li> <li>Support prelaunch medical readiness by educating stakeholders on emerging data, treatment paradigms, and patient identification considerations </li> <li>Gather, synthesize, and communicate field insights (e.g., unmet needs, treatment patterns, clinical questions) to inform medical strategy </li> <li>Identify and engage developing and established KOLs under the guidance of senior team members </li> <li>Collaborate cross-functionally with internal partners to ensure aligned execution of field activities </li> <li>Represent Praxis at scientific congresses and medical meetings, capturing and sharing relevant insights </li> <li>Maintain up-to-date knowledge of CNS/neurology disease areas, clinical data, and competitive landscape </li> <li>Ensure all activities are conducted in compliance with regulatory requirements, company policies, and industry standards </li> </ul> Qualifications and Key Success Factors <ul> <li>Advanced clinical or scientific degree (PharmD, PhD, MD, NP, PA, or RN) </li> <li>Early to mid-career experience in medical affairs, clinical practice, clinical research, or related roles in biotech/pharma </li> <li>Strong ability to learn and communicate scientific and clinical information clearly and credibly </li> <li>Demonstrated ability to build professional relationships with healthcare providers </li> <li>Interest in developing field-based expertise, including insight gathering and scientific engagement </li> <li>Ability to manage multiple priorities with strong organization and attention to detail </li> <li>Willingness to travel extensively (~60–80%) </li> <li>Experience in neurology or CNS disorders preferred </li> <li>Exposure to payer/market access concepts is a plus </li> <li>Candidates with prior field-based experience and a demonstrated track record of independently driving site performance, influencing investigators, and improving trial execution may be considered at a higher level. </li> </ul> The physical and mental requirements of our roles include but are not limited to regular use of a computer, devices or other office equipment, clear communication, and occasional movement. You'll need comfort with screen work, basic hand coordination, and focus. Reasonable accommodations may be made to enable individuals with disabilities to perform these functions. Compensation & Benefits At Praxis, we believe that taking care of our people (and their people) is important, so we provide a world class benefits package to help you thrive.  This includes 99% of the premium paid for medical, dental and vision plans. We also provide company-paid life insurance, AD&D, disability benefits, and voluntary plans to personalize your coverage. Thinking about the future?  We match dollar-for-dollar up to 6% on eligible 401(k) contributions and sweeten the deal with long-term stock incentives and ESPP.  We provide a discretionary quarterly bonus, an extremely flexible wellness benefit, generous PTO, paid holidays and company-wide shutdowns.  Not to mention, you'll also be joining a phenomenal crew of colleagues who are smart, engaged and inspiring.  We aim high, collaborate hard, and produce results.  Let’s achieve the impossible together! To round out our world-class total rewards package, we provide annualized base salary compensation in the range listed below. These ranges reflect the base salary ranges the Company reasonably expects to pay for each level at the time of posting. Placement within the range will be based on job-related factors, including experience, qualifications, scope of responsibilities, and demonstrated track record of delivering results in similar roles. <div class="content-pay-transparency"><div class="pay-input"><div class="title">Annualized Base Salary</div><div class="pay-range">$145,000—$175,000 USD</div></div></div><div class="content-conclusion">Company Overview Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system disorders characterized by neuronal imbalance. At Praxis we share a common vision of reshaping the human condition into a more freeing and fulfilled existence by developing high impact medicines for patients and families affected by and living with complex brain disorders. Our core Values of Trust, Ownership, Curiosity and Results are foundational to every aspect of our business and are exemplified by each and every one of our team members. Diversity, Equity & Inclusion Guided by our core values, at Praxis Precision Medicines, Inc. we continue to DARE FOR MORE® to advance, promote, and champion diversity, equity, and inclusion by encouraging individuals to bring their authentic selves and perspectives to work each day. We are an equal opportunity employer and committed to providing opportunities to all qualified applicants without regard to race, religious creed, color, gender identity or expression, age, national origin, sexual orientation, disability, genetics, military service and veteran status, or any other characteristic protected by federal, state, or local laws. Attention: Job Scam Alert Praxis has recently become aware of fraudulent job recruitment postings from individuals claiming to represent Praxis. These postings seek financial information in connection with fraudulent opportunities for employment. If you suspect any fraudulent activity or misrepresentation in connection with a Praxis job opportunity, please report it to <a href="mailto:careers@praxismedicines.com">careers@praxismedicines.com</a>. Praxis does not accept unsolicited submissions from recruitment agencies for open positions. We ask all recruitment agencies to refrain from contacting any Praxis employee regarding any position. All unsolicited resumes submitted by recruitment agencies to any Praxis employee in any form or method will be deemed to be the property of Praxis, and Praxis explicitly reserves the right to hire those candidate(s) without any financial obligation to the recruitment agency.</div>

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Common Interview Questions And Answers

1. HOW DO YOU PLAN YOUR DAY?

This is what this question poses: When do you focus and start working seriously? What are the hours you work optimally? Are you a night owl? A morning bird? Remote teams can be made up of people working on different shifts and around the world, so you won't necessarily be stuck in the 9-5 schedule if it's not for you...

2. HOW DO YOU USE THE DIFFERENT COMMUNICATION TOOLS IN DIFFERENT SITUATIONS?

When you're working on a remote team, there's no way to chat in the hallway between meetings or catch up on the latest project during an office carpool. Therefore, virtual communication will be absolutely essential to get your work done...

3. WHAT IS "WORKING REMOTE" REALLY FOR YOU?

Many people want to work remotely because of the flexibility it allows. You can work anywhere and at any time of the day...

4. WHAT DO YOU NEED IN YOUR PHYSICAL WORKSPACE TO SUCCEED IN YOUR WORK?

With this question, companies are looking to see what equipment they may need to provide you with and to verify how aware you are of what remote working could mean for you physically and logistically...

5. HOW DO YOU PROCESS INFORMATION?

Several years ago, I was working in a team to plan a big event. My supervisor made us all work as a team before the big day. One of our activities has been to find out how each of us processes information...

6. HOW DO YOU MANAGE THE CALENDAR AND THE PROGRAM? WHICH APPLICATIONS / SYSTEM DO YOU USE?

Or you may receive even more specific questions, such as: What's on your calendar? Do you plan blocks of time to do certain types of work? Do you have an open calendar that everyone can see?...

7. HOW DO YOU ORGANIZE FILES, LINKS, AND TABS ON YOUR COMPUTER?

Just like your schedule, how you track files and other information is very important. After all, everything is digital!...

8. HOW TO PRIORITIZE WORK?

The day I watched Marie Forleo's film separating the important from the urgent, my life changed. Not all remote jobs start fast, but most of them are...

9. HOW DO YOU PREPARE FOR A MEETING AND PREPARE A MEETING? WHAT DO YOU SEE HAPPENING DURING THE MEETING?

Just as communication is essential when working remotely, so is organization. Because you won't have those opportunities in the elevator or a casual conversation in the lunchroom, you should take advantage of the little time you have in a video or phone conference...

10. HOW DO YOU USE TECHNOLOGY ON A DAILY BASIS, IN YOUR WORK AND FOR YOUR PLEASURE?

This is a great question because it shows your comfort level with technology, which is very important for a remote worker because you will be working with technology over time...